Request demo

Explore all methods and technologies

Ligand Growing
Pick additional interactions from the active site of your protein
Ligand Linking and Joining
Find linkers from real chemistry to join two ligands
Macrocyclization
Drug difficult binding pockets using ligand macrocyclization
R-Group replacement
Find novel, biologically relevant R-Groups for your molecules
Scaffold Hopping
Find novel cores and scaffolds for your molecule discovery projects
Spark Fragment Databases
An outstanding source of bioisosteres from real chemistry to generate new project ideas
Water Replacement
Pick up additional ligand-protein interactions by displacing crystallographic waters
Filter methods