Stabilization of the open conformation of Insulin-Regulated Aminopeptidase by a novel substrate-selective small molecule inhibitor

SHARE
Protein Science | 2024

Mpakali A., Georgaki G., Buson A., Findlay A.D., et al. Stabilization of the open conformation οf insulin-regulated aminopeptidase by a novel substrate-selective small-molecule inhibitor. Protein Science. 2024, 33(9):e5151. https://doi.org/10.1002/pro.5151

Related Science Resources

Structural basis for CCR6 modulation by allosteric antagonists
Nature Communications | 2024 Wasilko, D.J., Gerstenberger, B.S., Farley, K.A. et al. Structural basis for CCR6 modulation by allosteric antagonists....
Driving Optimization of Antibiotic Drug Design
Since its heyday in the 1950s, the discovery of new classes of antibiotics has decreased, dropping to zero in the 1990s and not recovering since...
Combined In Silico and In Vitro Evidence Supporting an Aurora A Kinase Inhibitory Role of the Anti-Viral Drug Rilpivirine and an Anti-Proliferative Influence on Cancer Cells
Pharmaceuticals (Basel) | 2022 Islam S, Teo T, Kumarasiri M, Slater M, Martin JH, Wang S, Head R., Combined In Silico and In Vitro Evidence Supporting...

Subscribe & Don't Miss Out

Receive our newsletter to be among the first to hear about product releases, case studies, opinion articles, events and more.