FieldTemplater™Decipher the binding mode of your molecules in the absence of crystallographic information
Article Discerning binding modes of diverse dipeptidyl peptidase IV binders in the absence of structural information on the targetIntroduction In early drug discovery it is often the case that the only information available about a biological target is its activity against...
Citation A pharmacophore-based approach to demonstrating the scope of alcohol dehydrogenasesBioorganic & Medicinal Chemistry | 2023 Katrina S. Madden, Peter M.T. Todd, Kouji Urata, Angela J. Russell, et al.; A pharmacophore-based...
Citation Exploring the anti-SARS-CoV-2 main protease potential of FDA approved marine drugs using integrated machine learning templates as predictive toolsINTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2022 Naila Attiq, Uzma Arshad, Simone Brogi, Nusrat Shafiq, Fazeelat Imtiaz, Shagufta...
Citation Field-based rational design of p300 histone acetyltransferase inhibitor and systematic evaluation as an anti-fibrotic agentCHEMICAL COMMUNICATIONS | 2020 Soo-Yeon Hwang, Soo-Yeon Park, Jung Yeon Hong, Soo Yeon Lee, Jae-Ho Shin, Younghwa Na, Myung Hyun Sohn, Ho-Geun...
Citation In Silico Screening for Novel Leucine Aminopeptidase Inhibitors with 3,4-Dihydroisoquinoline ScaffoldZiemska, J.; Solecka, J.; Jarończyk, M. In Silico Screening for Novel Leucine Aminopeptidase Inhibitors with 3,4-Dihydroisoquinoline Scaffold....
Citation Identification of a New Chemotype of Anti-Obesity Compounds by Ensemble ScreeningACS OMEGA | 2020 Hyunkyung Cho, Joo-Youn Lee, Sang Yoon Choi, Chaemin Lim, Min-Kyoung Park, Hyejin An, Jeong Ok Lee, Minsoo Noh, Seunghee Lee, Sanghee...
Citation Bioisosteric Replacement as a Tool in Anti-HIV Drug DesignPHARMACEUTICALS | 2020 Dick, A.; Cocklin, S. Bioisosteric Replacement as a Tool in Anti-HIV Drug Design. Pharmaceuticals 2020, 13, 36. https://doi.org/10.3390/ph13030036...
