Science Resources: Case study

Streamlining design for covalent inhibitors
Nathan Kidley† †Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract Medicinal chemistry has...
3D-QSAR study on JAK inhibitors
日本語で読む Nathan Kidley† † Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract Robust and predictive...
Addressing metabolic liabilities by bioisosteric replacements with Spark™
Anand Balupuri†, Giovanna Tedesco† †Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract Metabolic...
Pick new ligand-protein interactions from the active site with Spark™
日本語で読む In this case study we will use the new Spark docking feature of the Cresset bioisostere replacement and scaffold hopping tool to prioritize...
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