There is often a divide between computational results and synthetic accessibility in the identification process of alternative compounds. However, there is now a way to produce results more quickly and precisely, and to ultimately accelerate the research process.
Our article Chemical Reaction discusses:
- Scaffold hopping
- Case studies:
- Finding bioisosteres of DPP-IV inhibitors
- Identifying optimization routes
- Fragment reconnection
- Accessible chemistry
- Available synthetic chemistry
This article is taken from Innovations in Pharmaceutical Technology July 2016, pages 16-19. © Samedan Ltd