Request demo
Picture of Scott Midgley

Scott Midgley

Science Resources

Identify trends and patterns in high-ranking molecular scaffolds using clustering algorithms in Spark™
Spark is a well-established software solution for computational bioisosteric replacement. In fact, our customers tell us it’s the best scaffold...
Identifying novel inhibitors against tuberculosis
Scott Midgley†, Nathan Kidley† †Cresset, New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire, SG8 0SS, UK Abstract Fragment-based...
Orientate your proteins on ligand superimposition using the Flare™ Python API
The importance of protein and ligand orientation during 3D visualization The orientation of protein structures is a simple yet essential manipulation...
Adaptive Lambda Scheduling: A Method for Computational Efficiency in Free Energy Perturbation Simulations
Abstract Recent increases in the availability of computational power have improved the accessibility of ligand–protein relative binding free...

News Articles

Engaging Cresset Discovery to advance your small molecule design project
When you choose Cresset Discovery as your CRO you access a team of skilled computational and medicinal chemists. This is a large team of experienced...
Identifying novel inhibitors against tuberculosis
Fragment-based drug discovery is an evolving area of research with unique challenges in developing the hits into lead molecules. In this case...

Blog

Engaging Cresset Discovery to advance your small molecule design project
When you choose Cresset Discovery as your CRO you access a team of skilled computational and medicinal chemists. This is a large team of experienced...
Identifying novel inhibitors against tuberculosis
Fragment-based drug discovery is an evolving area of research with unique challenges in developing the hits into lead molecules. In this case...