Flare offers several tools that can help you align and analyze protein sequences. The protein sequence alignment in Flare is powered by the COBALT multiple alignment tool.
- Perform instant alignment of selected sequences across multiple proteins
- Easy undo of sequence alignments
- Control alignment by adding and removing constraints
- Align corresponding protein chains by grouping them
- Quick input and import of sequences
- Export Alignment for use in other experiments
- Calculate similarity scores instantly with a choice of methods
- Calculate residue frequencies from the alignments and visualize them as a frequency logo.
References and acknowledgements
J.S. Papadopoulos, R. Agarwala, COBALT: constraint‑based alignment tool for multiple protein sequences, Bioinformatics 2007, 23(9), 1073–1079